The spriting information I got

I am working on sprites and I ask my friend Buxie for help this is the
information he said to me:

I usually zoom the sprite to 2400*1608. when you finish you turn it back to 800*560.
Then you get a better sprite.

How about use small size pen?

Don't draw in 79x79

I draw every sprite in 240x240

When I finish, I shrink them to 80x80
then it will be good

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what does it mean I don';t want to have blurry sprite
n i'm using paint.net atm